Sovaldi: A clear step forward in Hep C treatment

How do I take SOVALDI?

SOVALDI is taken once a day as part of a combination therapy to treat chronic (lasting a long time) hepatitis C (Hep C) in adults. The table below shows SOVALDI combination therapy regimens based on a patient’s type of Hep C, called genotype. SOVALDI has been shown to work in genotypes 1, 2, 3, and 4. SOVALDI should not be taken alone.

SOVALDI combination therapy regimens

GENOTYPE
1 OR 4

SOVALDI,
once a day
+
Ribavirin,
twice a day
+
Peginterferon alfa,
once a week
GENOTYPE
2

SOVALDI,
once a day
+
Ribavirin,
twice a day
GENOTYPE
3

SOVALDI,
once a day
+
Ribavirin,
twice a day

The table above applies to people with Hep C with or without HIV-1. For genotype 1 patients who cannot take peginterferon alfa, a 24-week regimen of SOVALDI plus ribavirin may be considered. Speak to your healthcare provider for more information.

How will I know if I am cured?

Cure means the Hep C virus is not detected in the blood when measured with a blood test by your healthcare provider 3 months after treatment is completed.

Taking your medicines

SOVALDI

SOVALDI tablet (400 mg)
not actual size
  • Take 1 tablet of SOVALDI 1 time each day only, with or without food.
  • Take SOVALDI exactly as your healthcare provider tells you to take it. Do not change your dose unless your healthcare provider tells you to.
  • Do not stop taking SOVALDI without first talking with your healthcare provider. If you think there is a reason to stop taking SOVALDI, talk to your healthcare provider before doing so.
  • If you miss a dose of SOVALDI, take the missed dose as soon as you remember the same day. Do not take more than 1 tablet (400 mg) of SOVALDI in a day. Take your next dose of SOVALDI at your regular time the next day.
  • If you take too much SOVALDI, call your healthcare provider or go to the nearest hospital emergency room right away.

Ribavirin

Ribavirin is taken by mouth twice daily with food. Your healthcare provider will determine your ribavirin dose based on your weight. Patients with renal impairment may require a lower dose. Discuss with your healthcare provider.

Peginterferon Alfa

Peginterferon alfa is an injection given under the skin once per week. If you have genotype 1 or 4, talk to your healthcare provider for specific dosing instructions.

Questions About Treatment?

In addition to your healthcare provider, Onward™ is here to help you move forward. Our SOVALDI Educators are here to provide answers and encouragement along the way, so you can stay focused on reaching your treatment goals. Learn more and sign up for Onward.

SOVALDI is a prescription medicine used with other antiviral medicines to treat chronic (lasting a long time) hepatitis C genotype 1, 2, 3, or 4 infection in adults. It is not known if SOVALDI is safe and effective in children under 18 years of age.

Important Safety Information

What should I tell my healthcare provider before taking SOVALDI?

  • If you have: liver problems other than hepatitis C infection; had a liver transplant; severe kidney problems or are on dialysis; HIV; any other medical condition; are pregnant or plan to become pregnant; or if you are breastfeeding or plan to breastfeed. It is not known if SOVALDI passes into your breast milk.
  • If you take amiodarone (Cordarone®, Nexterone®, Pacerone®), rifampin (Rifadin®, Rifamate®, Rifater®), St. John’s wort or a product that contains St. John’s wort. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how SOVALDI works.

You should not take SOVALDI if you also take other medicines that contain sofosbuvir (HARVONI®).

What are the most common side effects of SOVALDI?
For SOVALDI used in combination with ribavirin they include tiredness and headache and for SOVALDI used in combination with peginterferon alfa and ribavirin they include the additional side effects of nausea, difficulty sleeping, and low red blood cell count.

SOVALDI, the SOVALDI logo, HARVONI, ONWARD, the ONWARD logo, SUPPORT PATH, the SUPPORT PATH logo, GILEAD, and the GILEAD logo are trademarks of Gilead Sciences, Inc., or its related companies. All other trademarks referenced herein are the property of their respective owners.
©2016 Gilead Sciences, Inc. All rights reserved. SVDC0302 12/16

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SOVALDI is a prescription medicine used with other antiviral medicines to treat chronic (lasting a long time) hepatitis C genotype 1, 2, 3, or 4 infection in adults. It is not known if SOVALDI is safe and effective in children under 18 years of age.

Important Safety Information

What should I tell my healthcare provider before taking SOVALDI?

  • If you have: liver problems other than hepatitis C infection; had a liver transplant; severe kidney problems or are on dialysis; HIV; any other medical condition; are pregnant or plan to become pregnant; or if you are breastfeeding or plan to breastfeed. It is not known if SOVALDI passes into your breast milk.
  • If you take amiodarone (Cordarone®, Nexterone®, Pacerone®), rifampin (Rifadin®, Rifamate®, Rifater®), St. John’s wort or a product that contains St. John’s wort. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how SOVALDI works.

You should not take SOVALDI if you also take other medicines that contain sofosbuvir (HARVONI®).

What are the most common side effects of SOVALDI?
For SOVALDI used in combination with ribavirin they include tiredness and headache and for SOVALDI used in combination with peginterferon alfa and ribavirin they include the additional side effects of nausea, difficulty sleeping, and low red blood cell count.