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Recognize possible side effects—and know what to do about them

You may experience side effects while taking a SOVALDI combination therapy regimen. These are not all the possible side effects of SOVALDI. For more information, ask your healthcare provider or pharmacist.

SOVALDI + ribavirin regimen

Most Common Side Effects Tips
Tiredness

Do your hardest chores when you have the most energy.

Take short naps—20 minutes or less, and not close to bedtime.

Headache

Drink water. Limit coffee, tea, and soda with caffeine.

Avoid bright lights, loud noises, and bad smells.

SOVALDI + peginterferon alfa + ribavirin regimen

Most Common Side Effects Tips
Tiredness

Do your hardest chores when you have the most energy.

Take short naps—20 minutes or less, and not close to bedtime.

Headache

Drink water. Limit coffee, tea, and soda with caffeine.

Avoid bright lights, loud noises, and bad smells.

Nausea

Avoid spicy, greasy, and fried foods.

Try to eat smaller meals throughout the day, instead of 2 or 3 big meals.

Difficulty sleeping

Try to go to sleep at the same time every night.

Limit distractions—turn off your TV, computer, or other devices an hour or 2 before bedtime.

Low red blood cell count

Talk with your healthcare provider if you think you have symptoms of low red blood cell count. These include shortness of breath, tiredness, pale skin, and chills. He or she can use a test to measure your red blood cell count.

If the count is low, follow your healthcare provider’s instructions to adjust your treatment plan and make it as effective as possible.

SOVALDI is a prescription medicine used with other antiviral medicines to treat chronic (lasting a long time) hepatitis C genotype 1, 2, 3, or 4 infection in adults. It is not known if SOVALDI is safe and effective in children under 18 years of age.

Important Safety Information

What should I tell my healthcare provider before taking SOVALDI?

  • If you have: liver problems other than hepatitis C infection; had a liver transplant; severe kidney problems or are on dialysis; HIV; any other medical condition; are pregnant or plan to become pregnant; or if you are breastfeeding or plan to breastfeed. It is not known if SOVALDI passes into your breast milk.
  • If you take amiodarone (Cordarone®, Nexterone®, Pacerone®), rifampin (Rifadin®, Rifamate®, Rifater®), St. John’s wort or a product that contains St. John’s wort. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how SOVALDI works.

You should not take SOVALDI if you also take other medicines that contain sofosbuvir (HARVONI®).

What are the most common side effects of SOVALDI?
For SOVALDI used in combination with ribavirin they include tiredness and headache and for SOVALDI used in combination with peginterferon alfa and ribavirin they include the additional side effects of nausea, difficulty sleeping, and low red blood cell count.

SOVALDI, the SOVALDI logo, HARVONI, ONWARD, the ONWARD logo, SUPPORT PATH, the SUPPORT PATH logo, GILEAD, and the GILEAD logo are trademarks of Gilead Sciences, Inc., or its related companies. All other trademarks referenced herein are the property of their respective owners.
©2016 Gilead Sciences, Inc. All rights reserved. SVDC0302 12/16

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SOVALDI is a prescription medicine used with other antiviral medicines to treat chronic (lasting a long time) hepatitis C genotype 1, 2, 3, or 4 infection in adults. It is not known if SOVALDI is safe and effective in children under 18 years of age.

Important Safety Information

What should I tell my healthcare provider before taking SOVALDI?

  • If you have: liver problems other than hepatitis C infection; had a liver transplant; severe kidney problems or are on dialysis; HIV; any other medical condition; are pregnant or plan to become pregnant; or if you are breastfeeding or plan to breastfeed. It is not known if SOVALDI passes into your breast milk.
  • If you take amiodarone (Cordarone®, Nexterone®, Pacerone®), rifampin (Rifadin®, Rifamate®, Rifater®), St. John’s wort or a product that contains St. John’s wort. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how SOVALDI works.

You should not take SOVALDI if you also take other medicines that contain sofosbuvir (HARVONI®).

What are the most common side effects of SOVALDI?
For SOVALDI used in combination with ribavirin they include tiredness and headache and for SOVALDI used in combination with peginterferon alfa and ribavirin they include the additional side effects of nausea, difficulty sleeping, and low red blood cell count.